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Description

Renal iron overload in rats with diabetic nephropathy

Stockwell laboratory in 2012, represents an iron-dependent, non-apoptotic cell death modality distinguished by intracellular iron accumulation and lipid peroxidation, culminating in cell membrane disruption and cellular demise (13)

The forward pathway is present in bacteria such as Escherichia coli and Bacillus subtilis and can transfer sulfhydryl groups from cysteine to homocysteine