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indeed, some tumors use fatty acid oxidation (FAO) as the main source of energy and express high levels of FAO enzymes

The gate is broader than the norm, and paired with the eating disorder and alcohol-dependence gates it builds a meaningful mental-health-adjacent safety net without requiring a formal PHQ instrument

MT-II activates all four receptors at overlapping concentration ranges, making it a useful pan-agonist tool when a research protocol requires broad melanocortin engagement rather than receptor isolation