does semaglutide cause acid reflux Is Heartburn a Side Effect of Ozempic? What to Know Feeling nauseous after your GLP-1

In Vivo Assessment of Drug Interactions Effects of Sitagliptin on Other Drugs In clinical studies, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, digoxin, warfarin, or an oral contraceptive (ethinyl estradiol and norethindrone) (Table 4), providing in vivo evidence of a low propensity for causing drug interactions with substrates of CYP3A4, CYP2C8, CYP2C9, P-gp, and organic cationic transporter (OCT)

I'm not surprised there was little agreement on not re-starting agents that have been the focus of overdose, I see it all the time -- it is a complicated issue

"GLP-1 Drugs Cost and Savings." goodrx.com

This can lead to dehydration, making side effects worse