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J Am Acad Dermatol 72:10471053 Tanaka M, Sawada M, Kobayashi K (2011) Key points in dermoscopic differentiation between lentigo maligna and solar lentigo

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Overlap of the R152H variant backbone with wild-type was performed in the panel on the right, where the major conformational change in the loop around His152 was colored (WT as in pale pink and R152H as in red)