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Another phase II trial (PACIFIC-STROKE) evaluating the safety and efficacy of three doses of asundexian (10 mg, 20 mg, and 50 mg) in non-cardioembolic ischemic stroke did not show the efficacy of asundexian in reducing the composite of ischemic stroke and covert brain infarction in comparison with placebo [25]

Having carboxyl, amino, and imidazole groups as major structural components, His has been considered as a versatile chelator of metals (such as Ni) in plants (Callahan et al., 2003

GLP-1 RAs are drugs that imitate the function of natural GLP-1, a hormone in the intestine that controls glucose metabolism and feelings of fullness

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