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Nonsteroidal antiinflammatory drug (NSAID) Aspirin Aspirin, a commonly used NSAID, primarily works by inhibiting cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which in turn blocks thromboxane A 2 synthesis [124]

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It is used in conditions that involve oxidative stress, from Parkinsons disease to chronic obstructive pulmonary disease, and some cancer protocols use it to protect healthy cells from the side effects of chemotherapy and radiation

GSTP1 Ile105Val may be associated with an increased risk of CRC (118,116)