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An innovative approach to using IGF signalling pathways to target cancer is to use them to direct therapies to the tumour, for example, they can be conjugated to nanoparticles to enhance targeting and penetration of the tumour (Zhou et al., 2015)

A pilot clinical trial on L-carnitine supplementation in combination with motivation training: effects on weight management in healthy volunteers

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Discontinuation rates within the first year are consistently reported between approximately 45 and 75% (Sikirica et al., 2017