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The secretion of TNF- and IL-1 induced by HMGB1 in PR cells was blocked by FPS-ZM1 (an inhibitor of the AGER), thus reversing the degeneration of PR in rd1 mice ( 2.2 Microglia As the specialized resident macrophages in the neural retina, microglia constitute a primary population of glial cells ( Despite the absence of consensus on the mechanisms underlying microglial ferroptosis, several genes implicated in this process have been identified
PK activity measurements were performed as described (17)
& Aung, P
More compelling evidence is lacking
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