The binding of solTNF to the cognate receptor results in the procurement of the TNF adaptor protein (TNF receptor-associated death domain -TRADD), which leads to the binding of other cytosolic adaptor proteins like FAS-associated death domain (FADD), TNF receptor-associated factor 2 (TRAF2), and receptor-interacting protein (RIP)
For searching, the full-mix function of the TMTpro modification with the fixed modification of carbamidomethylation on cysteine was used
[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Obi P.C., Njoku G.H., Mbaike A.C., Ihim A.C., Nwako O.F., Anyanwu A.C., Ohiri J.U., Nwazor E., Ubani B.C., Ogbonna S.U., et al
ROS, either derived from an extracellular source or intracellularly generated, controls a dose-dependent mitochondrial distribution and function through the p38 pathway (Brooks et al., 2022)