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10.1016/j.clpt.2005.12.307 36 PiniL

People who are vitamin B12 deficient are often treated with vitamin B12 injections because they have the fewest barriers to absorption

doi: 10.1186/1471-230X-12-170 111

In the United States, synthetic semaglutide API is generally regulated as a drug substance under the FDA's complex drug substance guidance for peptides, supporting 505(b)(2) New Drug Applications or Abbreviated New Drug Applications (ANDAs) for finished dosage forms, with stringent requirements for physicochemical characterization, impurity profiling (including diastereomers and truncated sequences), and bioequivalence demonstration