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Though this is harder to separate from placebo, sleep improvements, or just normal training adaptation

The alcohol acts as a preservative, preventing the growth of bacteria in the vial after it has been punctured

This effect is manageable but may be more pronounced in initial weeks

Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times