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The largest research comes from the STEP-1 trial, which included 1,306 participants taking Semaglutide and 655 receiving a placebo

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A health plan CEO recently said in the Washington Post, and he said about GLP-1 medications for obesity "Everybody intuitively believes these medications create long-term health benefits, but the evidence hasnt yet demonstrated that paying todays prices generates enough downstream savings, There are no brand-name drugs currently marked in the U.S.to treat chronic diseases which lower total medical expenses

The New England Journal of Medicine, 391 (2), 109121