Studying the transcriptome of the ageing brain revealed substantially more prominent changes in neuroglia, and in astroglia in particular, when compared to neurones

Management of Iron Deficiency Anemia There is clear evidence to support prompt treatment in all patients with iron deficiency anemia because it is known that treatment improves quality of life and physical condition as well as alleviates fatigue and cognitive deficits.8-20 Although clear evidence is lacking, iron deficiency without anemia is associated with RLS and chronic fatigue, and treatment alleviates these symptoms.7,14-18 In CHF, iron replacement therapy has been shown to be beneficial, even when anemia is not present.8,12-14 Thus, the decision to treat iron deficiency in a patient without manifest anemia must be made on an individual basis.53,54 The treatment of iron deficiency anemia in patients with CKD, CHF, or cancer should be undertaken in conjunction with the appropriate specialists because different guidelines may apply

40 In patients with T2DM, the SURPASS-2 trial compared tirzepatide with semaglutide 1 mg (both as add-on therapies to metformin) and found tirzepatide was either noninferior or superior at all doses (5 mg, 10 mg 15 mg), for both HbA 1c reduction and weight loss at 40 weeks
GLP-1 Weight Loss Projection & Timeline Calculator *the weight loss and timeline projection calculator is based on average results from clinical studies and is dose dependent and medication dependent