Liraglutide vs Retatrutide: Cost and Access Head-to-Head At a glance Liraglutide / FDA-approved since 2014 (Saxenda for obesity, Victoza for type 2 diabetes) Retatrutide / Investigational, Phase 3 trials ongoing (estimated completion 2025-2026) SCALE trial weight loss / 8.0% mean body-weight reduction at 56 weeks with liraglutide 3.0 mg Phase 2 trial weight loss / 24.2% mean body-weight reduction at 48 weeks with retatrutide 12 mg Liraglutide generic retail cost / approximately $25-$100 per month for generic versions Saxenda branded cost / approximately $1,300-$1,500 per month without insurance Retatrutide cost / not commercially available
Its also cheaper to use less of any drug, which could make microdosing more appealing to patients who are paying out-of-pocket
It is sun protection, smoking cessation, adequate sleep, hydration, sufficient dietary protein, and for the women who are appropriate candidates systemic hormone therapy, which independently improves dermal collagen, skin thickness, and elasticity
Nrf2 can bind to the AREs in proteasomal gene promoter, which plays important roles in the degradation of DRP1
