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Since semaglutide slows stomach emptying, taking levothyroxine before breakfast (at least 1 hour before) ensures the thyroid hormone is absorbed in the upper small intestine before GLP-1 effects peak

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In 2023, semaglutide was the best-selling drug in the United States with nearly $14 billion in sales.1 There are an estimated 100 million obese adults in America, and an additional 37 million who may also be eligible to use medications like GLP-1s to manage chronic conditions

If you are taking compounded versions of these drugs, please heed the FDA's advice