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Despite recent advances in GLP-1R structure elucidation, detailed mechanistic understanding of how different peptides generate profound differences in G protein-mediated signalling is still lacking

648 In addition, treatment with liproxstatin-1 mitigates hypersensitivity reactions, reduces iron levels, reduces spinal cord lipid peroxidation, and prevents CCI-induced mitochondrial morphological changes, 648 suggesting that ferroptosis may be a potential therapeutic target for neuropathic pain