These agonists have been a part of successful clinical trials which showed that they assist in improvement in liver inflammation as well as insulin sensitivity
whereas nonselective immunosuppressants, which comprise glucocorticoids, cyclophosphamide, antimetabolites such as methotrexate and leflunomide, as well as herbal extracts like tripterygium wilfordii and sabia japonica maxim, exhibit a broader spectrum of effects, impacting multiple aspects of the immune system (242, 243) Although immunosuppressants are effective in reducing the overreaction of the immune system to pathological environments such as hypoxia, the accompanying heightened risk of complications, such as the development of malignant tumors, infectious diseases, and osteoporosis, underscores the need for an ideal immunosuppressant agent that is not only highly selective and fast-acting but also efficacious, with the capability to reverse its effects upon drug discontinuation, and possesses minimal side effects without compromising normal immune function
It should be used under the guidance of a physician or nutritionist to ensure safety and effectiveness
Y cada vez se va mejorando ms la eficacia y bajando todos los efectos adversos, que son gastrointestinales ms que nada, pero es una droga segura, que tambin baja el riesgo cardiovascular", concluye
