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Description

Biochem Biophys Res Commun (2018) 495(1):103440

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Glp-1r / mice had no insulinotropic response to EX-4 compared to the robust insulin secretion peaks seen in the hGLP-1R and mGlp-1r animals during the IPGTT ( Figure 3B )

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In the experiments with GLP-1R or GCGR antagonists, DIO C57BL/6J male mice were randomized in groups to receive the different treatments

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this effect results from a broad range of effects on appetite, weight, palatability, and the reward-seeking pathway in the central nervous system

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