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However, none of the case reports included long-term follow-up, making it difficult to assess any delayed complications

Zepbound has the same active ingredient as Mounjaro (tirzepatide), but is approved by the FDA only for weight loss

Saki N, Sarhangi N, Afshari M, Bandarian F, Meybodi HA, Hasanzad M (2020) MTNR1B common genetic variant is associated with type 2 diabetes mellitus risk

Furthermore, significantly elevated branch-chain fatty acids (BCFA), which are metabolic products of protein breakdown have been hypothesized to induce epithelium inflammation ( These microbial alterations coincided with PTSD symptomatology, BBB dysfunction and hippocampal neuroinflammation, which was confirmed by increased proinflammatory cytokine levels IL-1 and IL-6 (Tanelian et al., 2023)