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We analyzed 34 randomized clinical trials comparing: Continuous positive airway pressure (CPAP) GLP-1 receptor agonists No active intervention Here is what the evidence shows: CPAP remains the most effective therapy for reducing AHI GLP-1 receptor agonists produce clinically meaningful BMI and HbA1c reductions Blood pressure effects were inconsistent Respiratory and metabolic domains behave differently This is not a competition between CPAP and GLP-1 therapy

The final word: Hims ad is an offensive move against the pharma industry ( albeit a prediction we got right in our Health Trends to Watch in 2025 report ) for their high medication prices, but it will be pitted against drugmakers own campaigns during the Super Bowl

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Indirect Anti-Fibrotic Mechanisms Incretin agonists likely also exert anti-fibrotic activity by indirect mechanisms