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4 Nrf2 binds antioxidant response elements (AREs) and induces phase II detoxification enzymes, including glutathione S transferases (GSTs), nicotinamide adenine dinucleotide (phosphate) hydrogen [NAD(P)H] quinone oxidoreductase 1 (NQO1), heme oxygenase 1 (HO-1), and enzymes for GSH synthesis

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This novel medication will likely be used in instances similar to GLP-1 RAs especially in patients with diabetes with high A1Cs and patients with diabetes with a compelling need to lose weight