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Emerging data suggest that ferroptosis is one, if not the main, driver of cell death in cancer and neurodegenerative diseases like Parkinsons disease, Alzheimers disease, and Friedreichs ataxia [15, 45]

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These results suggest that the developmental stage of LSCs is a key factor for therapeutic advantage in acute liver failure (113)

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However, the risk of severe allergic reactions and the time-consuming nature of these treatments limit their routine use [65]

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