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Some people are born with lymphatic system problems (primary lymphedema), but most cases develop after cancer treatment, surgery, radiation, infection, or injury (secondary lymphedema)

Most people regain 510% of weight lost within the first 3 months after stopping, then stabilize if lifestyle habits remain consistent

Patients who are currently taking medications for diabetes or insulin resistance should monitor their blood sugar closely when starting this supplement, as the combination may lead to hypoglycemia, requiring a medication dosage adjustment by a healthcare provider

doi: 10.3389/fimmu.2023.1107670 Received 25 November 2022 Accepted 30 January 2023 Published 09 February 2023 Volume 14 - 2023 Edited by Jens Staal, Ghent University, Belgium Reviewed by Ping Jiang, Shanghai University of Traditional Chinese Medicine, China