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People taking GLP-1 medications commonly report reduced food cravings, less emotional eating, and a quieting of the constant mental preoccupation with food that researchers call "food noise." Animal studies have also shown that GLP-1 receptor activation reduces the rewarding properties of high-calorie food in the brain findings confirmed in a landmark randomized, placebo-controlled neuroimaging study in humans ( van Bloemendaal et al., Diabetes, 2014 )

The prescribing clinician should always direct the actual protocol

As seen in Figure 1 and 2, there is a distribution of weight change after cessation of GLP1-RA therapy

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