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Risk of adverse events with liraglutide in heart failure with reduced ejection fraction: a post hoc analysis of the FIGHT trial
PURINE CATABOLISM In addition to GSH redox coupling mechanism and NO signaling, purine catabolism ( Figure 2 ) may be a previously unappreciated component of the homeostatic response of mitochondria to oxidant stress and may play a critical role in slowing progressive mitochondrial dysfunction in certain disease states (Kristal et al., 1999)
a , HEK293T cells expressing GLP-1R (n = 3 independent biological replicates per group)
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