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Peptides are not inherently fragile, but they are chemically reactive

Intermuscular adipose tissue-derived inflammatory adipokines, exacerbated by aging, obesity, and sedentary behavior, promote both fat accumulation and chronic inflammation within skeletal muscle, driving adipogenic differentiation at the expense of myogenesis and thereby contributing to reduced muscle quality and increased metabolic risk [81]

Sun Y, Zhang P, Wang X, Al-Zahrani FAM, de Leeuw NH, Lin L

Ethics declarations All animal experiments were approved by the Animal Research Committee of Keio University and were performed in accordance with relevant guidelines and regulations (Institutional Guidelines on Animal Experimentation at Keio University)