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19, 20 The latter observation led to a recently completed phase I trial of BSO+L-PAM given with stem cell support in the New Approaches to Neuroblastoma Therapy (NANT) consortium that has safely dose-escalated L-PAM given with BSO to myeloablative L-PAM doses, with the stem cell infusions overcoming the expected hematopoietic toxicity (www.NANT.org

Again, no significant change in transcript abundance was observed in infested susceptible plants when the same pair of primers unique to the genes was used for PCR