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Nakahata, Y
If youve been searching for AOD-9604 lately, youre probably trying to answer some practical questions: Does it actually work for fat lossor is it hype
The analysis of the optimized structures of the MichaelisMenten complex indicate that the polar residues at position 13 (Cys or Ser) stabilize the deprotonated GS , which in turn acts as the catalytic Brnsted base and abstracts the proton at position C2 of substrate 7 (Extended Data Fig
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