Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration
These include the clearance of potentially detrimental metabolites and protein fragments, such as soluble A, from the brain [14], influencing tau protein dynamics [8], supporting the function of the blood-brain barrier (BBB) [15], maintaining synaptic integrity [16], consolidating memory [17], modulating glial activation [18], and regulating neuroinflammation [19]
Garnett KE, Chapman P, Chambers JA, Waddell ID, Boam DSW
What you put on your plate matters just as much as whats happening inside your body. She breaks down the top foods to pile your plate with or leave on the shelf