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Even more intriguing is the fact that none of the inclusion criteria for the above-mentioned studies encompassed tumour markers to potentially discard any ongoing or potential tumour process that, obviously, IGF-1 could accelerate

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GHRP-6 and Hexarelin are earlier ghrelin-receptor agonists that act on the same receptor as Ipamorelin but trigger broader endocrine responses, including cortisol, prolactin, and ACTH elevations, which limits their usefulness as clean ghrelin-pathway reference tools

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