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For persistent irritation, consider formulation issues rather than peptide intolerance

Journal of Neurology, 272 (1), 2

It is used in foods to prevent oxygen from destroying vitamin c and is used in doughs to reduce mixing time

While GHK-Cu is generally well-tolerated in topical research, certain contraindications or precautions should be considered, especially for systemic research or in specific populations: Systemic Research: For systemic applications, GHK-Cu is generally not recommended for subjects who are pregnant, breastfeeding, have active cancer, or suffer from Wilsons disease (a condition involving copper accumulation)