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2021, doi: 10.7570/jomes21071.

Never exceed conservative dosing: Doses above 5060 mcg/day lack robust clinical research support and may substantially increase adverse effect risk [2]

In conditions like ME/CFS, researchers have discovered a fascinating and troubling phenomenon: patients often have normal levels of Vitamin B12 in their standard blood tests, but significantly depleted levels of B12 in their cerebrospinal fluid (CSF)

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