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Some of the most well-known GLP-1 medications include: Liraglutide (Saxenda, Victoza) Semaglutide (Ozempic, Wegovy, Rybelsus) Dulaglutide (Trulicity) Tirzepatide (Mounjaro) also a GIP agonist These medications have shown remarkable success in clinical trials and real-world use for both glycemic control and weight loss

Strength training, in particular, can increase muscle mass and support a higher resting metabolic rate

But they stress that they are even more effective when combined with lifestyle changes, such as the ones they have been nudging us towards for years

Patients can often maintain their weight loss with a lower dose after initial success, which can help balance effectiveness with tolerability. According to Lilly, both trials met their primary and all key secondary endpoints