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tuberose methanolic root extract (PTME) as a potential herbal treatment on the liver homogenates of alloxan-induced diabetic rats, it was reported that PTME possessed an abundance of flavonoids and significantly reduced DPP-IV activity in a time-dependent manner from 16 DPP-IV activity in a time-dependent manner fromto 4 M/unit as compared with alloxan control (17.5 M/unit) within a period of 40 days, which proved that PTME was a promising candidate to cure DPP-IV-induced liver disorders (84)

When the vagus nerve fails to properly regulate the autonomic nervous system, patients become locked in a chronic sympathetic ("fight or flight") state