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Inhibition of CD38 has been shown to alleviate fructose-induced cell death and ERS in primary hepatocytes (Lee et al

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GSH can also reduce glutaredoxins (Grxs), which are small Trx-like proteins that further shuttle the electrons to various destinations, often but not always functioning analogous to Trxs (Fernandes and Holmgren, 2004

Glutathione (L--glutamyl-L-cysteinyl-glycine) is the primary intracellular antioxidant tripeptide, functioning as a substrate for glutathione peroxidase (GPx) and glutathione S-transferase (GST) enzymes in redox homeostasis and xenobiotic detoxification research models