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A patient losing 35 kg on retatrutide may lose more lean mass in absolute terms than a patient losing 20 kg on Mounjaro, even if the percentage of lean mass lost is similar
Tirzepatide , the dual GIP/GLP-1 receptor agonist, has demonstrated mean heart rate increases of approximately 2-4 beats per minute in the SURPASS clinical trial program, as reflected in the Mounjaro and Zepbound prescribing information
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