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But theres some good news for the needle-averse: The FDA has already approved one oral GLP-1 agonist, and more are being developed for obesity specifically

Vitamin B1, B6 and Cyanocobalamin Injection Treatment of severe vitamin B12 deficiency, particularly, and vitamin B1 and B6 deficiencies, which could cause neurological complications of various origins (e.g., absorption deficiency, insufficient diet, convalescence)

Seven glucagon-like peptide-1 receptor agonists and polyagonists for weight loss in patients with obesity or overweight: an updated systematic review and network meta-analysis of randomized controlled trials

In fact, obesity in HFrEF patients was associated with increased risk of heart failure hospitalisation [8]