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Nature 632, 139146

Astrocytes in ALS show many signs of functional decline, for example they demonstrate abnormal Ca 2+ signalling, 573 impaired secretion of neuroprotective glial-derived neurotrophic factor, 574 as well as reduced lactate production

A 2018 rat study showed that it increased GH receptor expression in tendon cells and activated key growth pathways, making tissues more responsive to circulating GH