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The elderly population is more susceptible to OS, caused by a deterioration in the efficacy of their endogenous antioxidant system and causes failure of several defense mechanisms to respond to reactive species (ROS, RNS)

[47] Antroduodenal manometry aids in differentiating between myopathic (scleroderma, amyloidosis) and neuropathic (diabetes mellitus) causes of impaired motility

These can be distinguished by the MRI appearance of enhanced nodular foci with surrounding edema, pial enhancement, and fludeoxyglucose uptake on PET-CT