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Remarkably, 5-cholesten-3-one, derived by oxidation of the 3-hydroxyl group of cholesterol, is not a substrate in spite of a structure of the A and B rings identical to that in 5-AD and 5-PD, in which the double bond isomerization occurs (Figure 2)
Glucagon-like peptide-1 modulates RAW264.7 macrophage polarization by interfering with the JNK/STAT3 signaling pathway
Aconitase activity To evaluate a functional consequence of oxidative stress, the activity of the redox-sensitive enzyme, aconitase, was measured using the Aconitase Assay Kit (Cayman Chemical, Ann Arbor, MI, USA) following the manufacturer's instructions
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