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Hyperhomocysteinemia is recognized as an independent risk factor for artherosclerosis of the coronary, cerebral, and peripheral vasculature

Figure 17: Large Tophus Seen as Soft Tissue Mass at the Elbow ) but in special cases, such as when gout needs to be separated from infection or tumor, magnetic resonance imaging (MRI) ( Figure 18: MRI of the Knee Showing Gouty Soft Tissue Mass and Erosion of the Kneecap ) or ultrasound ( Figure 19: Power Doppler Study Showing Gouty Inflammation at the Base of the 1st Toe ) will be helpful

Western blotting (WB) Whole-cell proteins were extracted from GC tissues and cells with RIPA lysis buffer (P0013B, Beyotime, China) supplemented with PMSF (P0100, Solarbio, China) and a protein phosphatase inhibitor (P1260, Solarbio, China)

Dietary supplementation with them has been shown to enhance protective effects, helping to manage oxidative stress and modulate inflammation