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doi: 10.1056/NEJMp1001578

Once anesthetized, the right knee joints of the animals were shaved, sterilized, and subjected to an intra-articular injection of collagenase type II

On November 8, 2023, the FDA approved Mounjaro (branded as Zepbound) for chronic weight management in overweight and obese adults with at least one weight-related condition (such as high blood pressure, type 2 diabetes or high cholesterol.) This approval is in addition to a reduced-calorie diet and increased physical activity

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