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The muscle loss associated with GLP-1 drug use is particularly concerning in older adults (50+) whose muscle mass and bone density is typically declining due to aging anyway, increasing the risk of fractures and falls, even fatal ones

Abbreviations NBH: National horticultural board BUN: Blood urea nitrogen BLA: Blood lactic acid ABTS: 2,2'-Azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) DPPH: 1,1-Diphenyl-2-picrylhydrazyl MCF-7: Michigan cancer foundation-7 HepG2: Hepatoma cells of human origin HeLa: Human cervical cancer cells VEGF: Vascular endothelial growth factor MDA: Malondialdehyde LPS: Lipopolysaccharide TNF-: Tumor necrosis factor IL-6: Interleukin-6 IL-1: Interleukin-1 beta NF-B: Nuclear factor kappa B DEAE: Diethylaminoethyl OFPS: Okra flower polysaccharide NO: Nitric acid COX: Cyclooxygenase LOX: Lipoxygenase HPMC: Hydroxypropyl methylcellulose NaCMC: Sodium carboxymethyl cellulose AEL: Abelmoschus esculentus CMC: Carboxymethyl cellulose References Rao SR, Nongsiang RH, Devi MK

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