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The prevalence of bullous pemphigoid was 0.0859% in total, with a trend toward a higher risk associated with vildagliptin use compared to the other DPP-4 inhibitors ( In total, however, the DPP-4 inhibitor class has demonstrated a good safety and tolerability spectrum that justifies the wide use of the class

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For uses and methods for the treatment of arthritis, e.g., intrasynovial administration may be employed, as described for other immunological agents in U.S