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In the latest international pooled analysis, the adverse associations of TMAO with certain cardiometabolic biomarkers have been elucidated, and the mechanisms of action, independent of renal function, warrant further investigation (96)

Some controlled trials report 10-15% reductions in liver fat with lipotropic supplementation over 8-12 weeks

Propensity score-matched pairs were created by matching two groups using the nearest-neighbor method with a 0.2 caliper width in the fluoroquinolone cohort and the older adult cohort