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It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

Reduced Appetite and Food Cravings Semaglutide's ability to reduce hunger corresponds to its efficacy as a weight-reduction medication

[17] Supporting Muscle Preservation During periods of caloric restriction, maintaining muscle mass becomes challenging

NICE NG19 recommends annual foot examinations for all people with diabetes, incorporating: 10-g monofilament testing (Semmes-Weinstein monofilament) to assess protective sensation at standardised foot sites Vibration perception using a 128-Hz tuning fork at the hallux Ankle reflex examination Visual inspection for structural deformities, skin changes, and ulceration Assessment of peripheral pulses (dorsalis pedis and posterior tibial) to evaluate vascular status Foot risk stratification (low, moderate, high risk, or active diabetic foot problem) Patients reporting neuropathic symptoms should undergo comprehensive neurological examination