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Storing the vial at the right temperature (3646F / 28C) and protecting it from freezing, heat, and light is essential to maintain its potency, safety, and effectiveness

PMID: 27593609, DOI: 10.1016/j.amjmed.2016.07.036

Reducing crude protein (CP) concentrations in the diet, while maintaining animal performance, has therefore been proposed as a strategy to decrease nitrogen excretion and lower feeding costs

While selenium deficiency is a major etiological factor of Keshan disease (54), the seasonal and annual variation in disease occurrence suggested that other factors, especially an infectious agent, might be involved in addition to selenium deficiency (55)