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Approximately 20% of patients could have evidence of cirrhosis, which was defined as liver-biopsy results showing a Metavir fibrosis score of 4 or an Ishak score of 5 or more, a FibroTest score of more than 0.75 and a ratio of aspartate aminotransferase to platelets of more than 2, or a FibroScan reading of more than 12.5 kPa

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They have this natural ability to expand in the stomach as and when mixed with liquid and it creates a feeling of fullness

Major degradation pathways to monitor are tryptophan oxidation (residue sensitive to UV light and oxidants), D-Phe 7 epimerization in basic media, and hydrolysis of the MT-II lactam bond in prolonged acidic media