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While NMDA receptors allow entry of Ca 2+ , AMPA receptors heterotetramer, which consists of four glutamate receptor subunits (GluR1-4), mediate the entry of Na + current into the neuron, thus resulting in rapid signal transmission ( Ketamine: One Drug, Many Uses Originally approved in 1970 as an anesthetic, ketamine thereafter earned notoriety as a recreational drug of abuse (Special K) because of its dissociative effects

Phytother Res 34(9):23512365 Hindam MO, Ahmed LA, Sayed NSE, Khattab M, Sallam NA (2024) Repositioning of baricitinib for management of memory impairment in ovariectomized/D-galactose treated rats: a potential role of JAK2/STAT3-PI3K/AKT/mTOR signaling pathway