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Methionine plays a role in breaking down fats, helping to prevent the buildup of fatty deposits in blood vessels that might cause coronary artery disease and blockages in the neck and legs

Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 1), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification

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